{"id":5461,"date":"2026-06-01T15:47:31","date_gmt":"2026-06-01T06:47:31","guid":{"rendered":"https:\/\/indna.co.kr\/?page_id=5461"},"modified":"2026-06-18T15:15:53","modified_gmt":"2026-06-18T06:15:53","slug":"dovetail-ffpe-assay","status":"publish","type":"page","link":"https:\/\/indna.co.kr\/?page_id=5461","title":{"rendered":"Dovetail FFPE Assay"},"content":{"rendered":"\t\t
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Dovetail FFPE Assay<\/div><\/div><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Dovetail\u00ae <\/sup><\/span>FFPE Assay<\/span><\/span><\/h2>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\nFFPE \uc0d8\ud50c\uc740 \uc554 \uc5f0\uad6c\uc5d0\uc11c \uac00\uc7a5 \ub110\ub9ac \ud65c\uc6a9\ub418\ub294 \uc911\uc694\ud55c \uc790\uc6d0\uc774\uc9c0\ub9cc, \ud575\uc0b0 \ubd84\ud574(degradation) \ubb38\uc81c\ub85c \uc778\ud574 \ub300\ubd80\ubd84\uc758 \uc720\uc804\uccb4 \ubd84\uc11d\u2014\ud2b9\ud788 \uad6c\uc870\uc801 \ubcc0\uc774(Structural Variants, SV) \ud0d0\uc9c0\uc5d0 \ud070 \uc5b4\ub824\uc6c0\uc774 \ub530\ub985\ub2c8\ub2e4.

\nDovetail\uc758 FFPE \uae30\uc220\uc740 \ubc14\ub85c \uc774\ub7ec\ud55c \ud55c\uacc4\ub97c \uadf9\ubcf5\ud569\ub2c8\ub2e4.<\/b>\n<\/span>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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Dovetail Genomics\ub294 linked-read \ub77c\uc774\ube0c\ub7ec\ub9ac \uc81c\uc791\uc744 \uc704\ud574 FFPE\uc5d0 \ucd5c\uc801\ud654\ub41c \uc6cc\ud06c\ud50c\ub85c\uc6b0\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4. Dovetail linked-read\ub97c \ud65c\uc6a9\ud558\uba74 \ucf54\ub529 \ubc0f \ub17c\ucf54\ub529 \uc601\uc5ed\uc758 \uc720\uc804\uccb4 \uc7ac\ubc30\uc5f4\uc744 \ud3ec\ud568\ud55c SV\ub97c \ub192\uc740 \ubbfc\uac10\ub3c4\ub85c \ud0d0\uc9c0\ud560 \uc218 \uc788\uc73c\uba70, \ub3d9\uc2dc\uc5d0 SNV, INDEL, CNV \ub4f1 \ub2e4\ub978 \ubcc0\uc774 \ubd84\uc11d\uc5d0\uc11c\ub3c4 \uae30\uc874 short-read \ubc29\uc2dd\uc758 \uc6b0\uc218\ud55c \uc131\ub2a5\uc744 \uadf8\ub300\ub85c \uc720\uc9c0\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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  • FFPE \uc0d8\ud50c \uc644\ubcbd \ud638\ud658 (Compatible with FFPE Samples)<\/strong>
    \uae4c\ub2e4\ub85c\uc6b4 \uace0\ubd84\uc790\ub7c9(High-molecular-weight) DNA \ucd94\ucd9c \uacfc\uc815\uc774 \ud544\uc694\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/li>
  • \uc77c\uad00\ub41c \ubd84\uc11d \uc131\ub2a5 (Consistent Performance)<\/strong>
    \ub2e4\uc591\ud55c \uc885\uc591(Tumor) \uc720\ud615\uacfc \uc5ec\ub7ec DNA \ud004\ub9ac\ud2f0 \uc870\uac74\uc5d0\uc11c \uc131\ub2a5 \uac80\uc99d\uc744 \uc644\ub8cc\ud588\uc2b5\ub2c8\ub2e4.<\/li>
  • \uc815\ud655\ud55c \ubcc0\uc774 \uc2dc\uadf8\ub110 \uc99d\ud3ed (Amplifies True-Variant Signal)<\/strong>
    SV \ud0d0\uc9c0 \ubbfc\uac10\ub3c4\ub97c \uadf9\ub300\ud654\ud558\uace0 \uc704\uc591\uc131(False positives) \ubc1c\uc0dd\uc744 \ucd5c\uc18c\ud654\ud569\ub2c8\ub2e4.<\/li>
  • \ud3ec\uad04\uc801\uc778 \uc720\uc804\uccb4 \uc7ac\ubc30\uc5f4 \ud504\ub85c\ud30c\uc77c\ub9c1 (Comprehensive Rearrangement Profiling)<\/strong>
    \ucf54\ub529 \uc601\uc5ed\uc758 \uc720\uc804\uc790 \uc735\ud569(Gene fusions)\uc740 \ubb3c\ub860, \ub17c\ucf54\ub529 \uc601\uc5ed\uc758 \uc778\ud578\uc11c \ud558\uc774\uc7ac\ud0b9(Enhancer hijacking) \uc774\ubca4\ud2b8\uae4c\uc9c0 \ubaa8\ub450 \ud0d0\uc9c0\ud569\ub2c8\ub2e4.<\/li>
  • \ud6a8\uc728\uc801\uc778 \ubcc0\uc774 \ud0d0\uc9c0 \uc6cc\ud06c\ud50c\ub85c\uc6b0 (Streamlines Variant Detection)<\/strong>
    \ub2e8 \ud55c \ubc88\uc758 \ubd84\uc11d(Single assay)\uc73c\ub85c SV, SNV, INDEL, CNV\ub97c \ubaa8\ub450 \ud30c\uc545\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.(Enhancer hijacking) \uc774\ubca4\ud2b8\uae4c\uc9c0 \ubaa8\ub450 \ud0d0\uc9c0\ud569\ub2c8\ub2e4.<\/li>
  • \uae30\uc874 NGS \uc778\ud504\ub77c \ud65c\uc6a9 (Fits Existing NGS Infrastructure)<\/strong>
    \uc0c8\ub85c\uc6b4 \uc7a5\ube44 \ub3c4\uc785 \uc5c6\uc774, \uae30\uc874\uc5d0 \uc0ac\uc6a9 \uc911\uc778 \ud45c\uc900 short-read \uc2dc\ud000\uc2f1 \ud50c\ub7ab\ud3fc\uacfc \uc644\ubcbd\ud558\uac8c \ud638\ud658\ub429\ub2c8\ub2e4.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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    FFPE \uc0d8\ud50c \ubd84\uc11d\uc758 \uc8fc\uc694 \ud55c\uacc4\uc810(Known Challenges With FFPE Samples)<\/span><\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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    \ud83d\udfe6 DNA Quality \uc81c\uc57d (DNA Quality Constraints)<\/strong><\/p>

    • DNA \ud488\uc9c8 \uc800\ud558\ub85c \uc778\ud574 Library complexity\uac00 \ub0ae\uc544\uc9c0\uba70, \uacb0\uacfc\uc801\uc73c\ub85c \ud655\ubcf4\ud560 \uc218 \uc788\ub294 Coverage\uc5d0 \ud55c\uacc4\uac00 \uc0dd\uae41\ub2c8\ub2e4.<\/li>
    • FFPE \ud2b9\uc720\uc758 Fragmented DNA\ub294 Long-read, OGM, TruPath\uc640 \uac19\uc740 \ucd5c\uc2e0 \ubd84\uc11d \uae30\uc220\uc5d0 \uc801\uc6a9\ud558\uae30 \uae4c\ub2e4\ub86d\uc2b5\ub2c8\ub2e4.<\/li><\/ul>

      \ud83d\udfe7 Gene Fusion \ud0d0\uc9c0\uc758 \ud55c\uacc4 (Gene Fusion Detection Limitations)<\/strong><\/p>

      • RNA \ud488\uc9c8\uc774 \ub0ae\uc73c\uba74 Breakpoint spanning read\uac00 \uc904\uc5b4\ub4e4\uc5b4, \uacb0\uacfc\uc801\uc73c\ub85c Gene fusion\uc744 \ub193\uce60(missed calls) \uc704\ud5d8\uc774 \ucee4\uc9d1\ub2c8\ub2e4.<\/li>
      • RNA Yield\uac00 \ub0ae\uc544 RNA-seq Library prep \uc790\uccb4\uac00 \uc2e4\ud328\ud558\uac70\ub098, Duplication rate\uac00 \ub192\uc740 \ud3b8\ud5a5\ub41c(biased) Library\uac00 \ub9cc\ub4e4\uc5b4\uc9c0\uae30 \uc27d\uc2b5\ub2c8\ub2e4.<\/li><\/ul>

        \u2b1c \uad6c\uc870\uc801 \ubcc0\uc774\uc758 \ub192\uc740 \uc704\uc591\uc131\ub960 (High False Positive SV Calls)<\/strong><\/p>

        • Library prep \uacfc\uc815\uc5d0\uc11c \uc778\uc704\uc801\uc73c\ub85c \ub9cc\ub4e4\uc5b4\uc9c4(artifactual) Chimeric read\uac00 \ub9ce\uc544\uc838, \uad6c\uc870\uc801 \ubcc0\uc774(SV) \ubd84\uc11d \uc2dc False positive(\uc704\uc591\uc131)\uac00 \ud06c\uac8c \uc99d\uac00\ud569\ub2c8\ub2e4.<\/li>
        • FFPE NGS \ub370\uc774\ud130\uc5d0\uc11c \ud754\ud788 \ub098\ud0c0\ub098\ub294 Coverage drop-out\uc774\ub098 Spike \ud604\uc0c1\uc774 SV Caller\uc758 \uc815\ud655\ud55c \ubd84\uc11d\uc744 \ubc29\ud574\ud569\ub2c8\ub2e4.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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          The Dovetail FFPE Solution<\/span><\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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          \uc77c\ubc18\uc801\uc778 Whole Genome Sequencing(WGS)\uc5d0\uc11c\ub294 \uad6c\uc870\uc801 \ubcc0\uc774(SV)\uc758 Breakpoint\uc5d0 \uc9c1\uc811 \ub9f5\ud551\ub418\ub294 Read\ub9cc\uc73c\ub85c Variant\ub97c \ud310\ubcc4\ud569\ub2c8\ub2e4. FFPE \uc0d8\ud50c\uc740 \uc560\ucd08\uc5d0 \ud655\ubcf4\ud560 \uc218 \uc788\ub294 Coverage\uc5d0 \ud55c\uacc4\uac00 \uc788\uc5b4 \uc774\ub7ec\ud55c Breakpoint-spanning read\uac00 \ud131\uc5c6\uc774 \ubd80\uc871\ud574\uc9c0\uae30 \uc26c\uc6b4\ub370, \uc774\ub294 \uacb0\uad6d \ubd84\uc11d\uc758 \ubbfc\uac10\ub3c4(Sensitivity)\ub97c \ub5a8\uc5b4\ub728\ub9ac\uace0 \uc704\uc591\uc131(False positive)\uc744 \ud06c\uac8c \uc99d\uac00\uc2dc\ud0a4\ub294 \uc6d0\uc778\uc774 \ub429\ub2c8\ub2e4.<\/span><\/span><\/p>

          Dovetail \uae30\uc220\uc740 Breakpoint-spanning read\ub294 \ubb3c\ub860 Breakpoint-flanking read\uae4c\uc9c0 \ubaa8\ub450 \ud65c\uc6a9\ud558\ub294 Library\ub97c \ud1b5\ud574 \uae30\uc874\uc758 \ud55c\uacc4\ub97c \uc644\ubcbd\ud788 \uadf9\ubcf5\ud588\uc2b5\ub2c8\ub2e4.<\/b>
          <\/span><\/span>\ud0d0\uc9c0 \ubc94\uc704(Detection window)\ub97c \uba54\uac00\ubca0\uc774\uc2a4(Megabase) \ub2e8\uc704\ub85c \ud655\uc7a5\ud558\uc5ec \ubd84\uc11d \ubbfc\uac10\ub3c4\ub97c \ud68d\uae30\uc801\uc73c\ub85c \ub192\uc778 \uacb0\uacfc, \uae30\uc874 WGS\uc758 Small variant(SNV, INDEL, CNV) \ubd84\uc11d \uc131\ub2a5\uc740 \uadf8\ub300\ub85c \uc720\uc9c0\ud558\uba74\uc11c\ub3c4 \uad6c\uc870\uc801 \ubcc0\uc774(SV)\ub97c \ud6e8\uc52c \ub354 \uc815\ubc00\ud558\uac8c \ud0d0\uc9c0(Calling)\ud560 \uc218 \uc788\uac8c \ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/b><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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          \uac15\ub825\ud558\uace0 \uc548\uc815\uc801\uc778 \uc131\ub2a5 (Robust Performance)<\/span><\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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          \ub2e4\uc591\ud55c \ud488\uc9c8, Tumor type, \uadf8\ub9ac\uace0 Tumor fraction\uc744 \uac00\uc9c4 FFPE \uc0d8\ud50c\ub4e4\uc744 \ub300\uc0c1\uc73c\ub85c Dovetail FFPE assay\ub97c \uc801\uc6a9\ud574 Library\ub97c \uc81c\uc791\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub97c 30X Genome coverage\ub85c \uc2dc\ud000\uc2f1\ud558\uc5ec \uc5fc\uc0c9\uccb4 \ub0b4(Intra-chromosomal) \ubc0f \uc5fc\uc0c9\uccb4 \uac04(Inter-chromosomal) \uad6c\uc870\uc801 \ubcc0\uc774\ub97c \ubd84\uc11d\ud55c \uacb0\uacfc, Dovetail FFPE\ub294 \ubaa8\ub4e0 \uc0d8\ud50c \uc870\uac74\uc5d0\uc11c \ud754\ub4e4\ub9bc \uc5c6\ub294 \uac15\ub825\ud55c \uc131\ub2a5\uc744 \uc785\uc99d\ud588\uc2b5\ub2c8\ub2e4. \ub098\uc544\uac00 \ub370\uc774\ud130\ub97c 10X Coverage\ub85c Downsampling\ud55c \uc870\uac74 \uc18d\uc5d0\uc11c\ub3c4 \ub6f0\uc5b4\ub09c \uc131\ub2a5\uc740 \uadf8\ub300\ub85c \uc720\uc9c0\ub418\uc5c8\uc2b5\ub2c8\ub2e4.
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          \uc55e\uc11c \ubd84\uc11d\uc5d0 \uc0ac\uc6a9\ub41c \uc885\uc591 FFPE \uc0d8\ud50c\uc740 Fresh frozen(\uc2e0\uc120 \ub3d9\uacb0) \uc870\uc9c1 \ud615\ud0dc\ub85c\ub3c4 \ud655\ubcf4\ub418\uc5b4 \uc788\uc5c8\uc2b5\ub2c8\ub2e4. \uc774 Fresh frozen \uc0d8\ud50c\ub85c Library\ub97c \uc81c\uc791\ud55c \ub4a4, FFPE \uc0d8\ud50c\uacfc \ub3d9\uc77c\ud55c Coverage \uc870\uac74\uc73c\ub85c Sequencing\uc744 \uc9c4\ud589\ud588\uc2b5\ub2c8\ub2e4. \uc774\ud6c4 Dovetail Analysis Portal\uc744 \ud65c\uc6a9\ud574 \uad6c\uc870\uc801 \ubcc0\uc774(SV)\ub97c \ubd84\uc11d(Calling)\ud558\uace0, \uc5fc\uc0c9\uccb4 \uac04(Inter-chromosomal) \ubcc0\uc774\uc5d0 \ub300\ud55c VAF(Variant Allele Fraction) \uac12\uc744 \uc0b0\ucd9c\ud588\uc2b5\ub2c8\ub2e4.<\/span><\/span><\/p>

          \uadf8 \uacb0\uacfc, Fresh frozen \uc0d8\ud50c\uacfc FFPE \uc0d8\ud50c \uac04\uc758 SV \ubd84\uc11d \uacb0\uacfc\ub294 Breakpoint \uc815\ud655\ub3c4(Precision)\uc640 VAF \ucd94\uc815\uce58 \ubaa8\ub450\uc5d0\uc11c \ub9e4\uc6b0 \ub192\uc740 \uc77c\uce58\uc728(Concordance)\uc744 \ubcf4\uc5ec\uc8fc\uc5c8\uc2b5\ub2c8\ub2e4.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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          Dovetail FFPE Assay Dovetail\u00ae FFPE Assay FFPE \uc0d8\ud50c\uc740 \uc554 \uc5f0\uad6c\uc5d0\uc11c \uac00\uc7a5 \ub110\ub9ac \ud65c\uc6a9\ub418\ub294 \uc911\uc694\ud55c \uc790\uc6d0\uc774\uc9c0\ub9cc, \ud575\uc0b0 \ubd84\ud574(degradation) \ubb38\uc81c\ub85c \uc778\ud574 \ub300\ubd80\ubd84\uc758 \uc720\uc804\uccb4 \ubd84\uc11d\u2014\ud2b9\ud788 \uad6c\uc870\uc801 \ubcc0\uc774(Structural Variants, SV) \ud0d0\uc9c0\uc5d0 \ud070 \uc5b4\ub824\uc6c0\uc774 \ub530\ub985\ub2c8\ub2e4. Dovetail\uc758 FFPE \uae30\uc220\uc740 \ubc14\ub85c \uc774\ub7ec\ud55c \ud55c\uacc4\ub97c \uadf9\ubcf5\ud569\ub2c8\ub2e4. Dovetail Genomics\ub294 linked-read \ub77c\uc774\ube0c\ub7ec\ub9ac \uc81c\uc791\uc744 \uc704\ud574 FFPE\uc5d0 \ucd5c\uc801\ud654\ub41c \uc6cc\ud06c\ud50c\ub85c\uc6b0\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4. Dovetail linked-read\ub97c \ud65c\uc6a9\ud558\uba74 \ucf54\ub529 \ubc0f \ub17c\ucf54\ub529 \uc601\uc5ed\uc758 \uc720\uc804\uccb4 […]<\/p>\n","protected":false},"author":208,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-5461","page","type-page","status-publish","hentry"],"yoast_head":"\nDovetail FFPE Assay - INDNA<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/indna.co.kr\/?page_id=5461\" \/>\n<meta property=\"og:locale\" content=\"ko_KR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Dovetail FFPE Assay - INDNA\" \/>\n<meta property=\"og:description\" content=\"Dovetail FFPE Assay Dovetail\u00ae FFPE Assay FFPE \uc0d8\ud50c\uc740 \uc554 \uc5f0\uad6c\uc5d0\uc11c \uac00\uc7a5 \ub110\ub9ac \ud65c\uc6a9\ub418\ub294 \uc911\uc694\ud55c \uc790\uc6d0\uc774\uc9c0\ub9cc, \ud575\uc0b0 \ubd84\ud574(degradation) \ubb38\uc81c\ub85c \uc778\ud574 \ub300\ubd80\ubd84\uc758 \uc720\uc804\uccb4 \ubd84\uc11d\u2014\ud2b9\ud788 \uad6c\uc870\uc801 \ubcc0\uc774(Structural Variants, SV) \ud0d0\uc9c0\uc5d0 \ud070 \uc5b4\ub824\uc6c0\uc774 \ub530\ub985\ub2c8\ub2e4. Dovetail\uc758 FFPE \uae30\uc220\uc740 \ubc14\ub85c \uc774\ub7ec\ud55c \ud55c\uacc4\ub97c \uadf9\ubcf5\ud569\ub2c8\ub2e4. Dovetail Genomics\ub294 linked-read \ub77c\uc774\ube0c\ub7ec\ub9ac \uc81c\uc791\uc744 \uc704\ud574 FFPE\uc5d0 \ucd5c\uc801\ud654\ub41c \uc6cc\ud06c\ud50c\ub85c\uc6b0\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4. 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